Sometimes they just won’t listen but you have to insist. he hasnt taken a bath since he was given the 2nd advocate. His bedding was covered in blood my poor baby looks like he been savaged. What alternatives are there? 48 hours after I applied the drug, Speckles began to act differently. Dont know if anyone is still reading these but I’m going through this now with my dog, is there anyway of reversing it? I’ve just got a prescription from my vet to buy another year’s supply of Advocate from PetMeds online, which I have been told by another vet is a ‘safe and trusted’ website. She did a day later and said she had spoken to the manufacturer who said that these claims were unfounded at the explanation for my dog was behavioural. 382, No. Some dogs may develop irritation at the site of the application. He stopped being as frantic almost right away but two weeks later is still occasionally bites his legs and cries. My dog has been taking this for a long time so he said she mustn’t carry the gene for this. Please email me at [email protected] or [email protected] Don’t use too much. Back legs not functioning, shaking, panting, crying tears, and the look in his eyes were saying, help me mom & dad!! 23, 2020). “But these haven’t yet been studied specifically in COVID-19 patients,” he says. His personality changes completely. yes it might work fine to many dogs but side effects are more common than Bayer & your vets makes out. Let mm now if you have gotten any response from Bayor. Has anyone heard of this? 2 years ago I applied advocate to my Yorkie, having done so for 8 years. Am absolutely astounded the difference in him. He would hide himself away and sit or stand fixed to the spot shaking all over .It would take an hour or so to get him over it. My husband is devastated and we have no idea where to go from here. What is the risk associated with Advocate? You will want to begin to control for secondary issues such as urinary tract infections and megacolon. He jumped in the sofa.. something he isnt allowed to do and become really aggressive baring his teeth, growling and lunging forward. I pray she comes out of this! Experts around the world are working to make that happen. Never again. 5 days on and she is struggling to walk, can barely lift her head and is not eating well. My vet just told me to keep an eye on him. Inactive & Dull. The problem is you would have to pay a lawyer to sue them. Cons to Using Advocate One of the cons to using any medication is the potential for side-effects and a negative reaction to the product itself. I will never use this product again. Unless you own a great Dane there is no need to apply the full amount. 1 hrs after applying Advantage, Gizmo had a big seizure. The dog I inherited over a year You are your loved one’s most important advocate during stroke recovery. i used when she was a puppy and How COVID-19 attacks the brain. He needs steroids and has had MRI, lumbar puncture and bloods. But he’s only 9 months and acts like he’s got arthritis. I hope you find some answers that help him. I’m scared to death as she is not herself. I can honestly say, I thought she was dying yesterday afternoon. What would be your advice – should I or shouldn’t I, and if not, what are the alternatives for preventing Lungworm? I’m glad that you decided to wash the Advocate off Maggie. Common side effects are hair loss, nausea, low blood counts, joint pain and neurological side effects such as weakness, numbness and tingling (which may be temporary during treatment or more permanent, depending on dosage and duration). Advocate 100% brings on seizures.. My chihuahua was prescribed advocate as a puppy for 4years he suffered seizures all along while i was giving him advocate drops. https://news.wsu.edu/2013/07/08/researcher-recognized-for-drug-reaction-discovery-in-dogs/, It’s a well known side effect, especially to dogs with the MDR1 Gene, Google MDR1. They said that the ivermectin in Advocate can cause seizures and other neurological problems because the gene causes hypersensitivity to that ingredient. She has been through a very difficult week. You might notice on each pack it has a weight range? Thank you for your information regarding using Advocate on Border Collies. Please contact me. After the first siezure she was taken to the vet but he had no answer to what may have caused this! A third negative to this product is that although it protects against fleas, it does not protect against ticks. The good news is that he is much better in himself and working well. I have a 15 week old puppy chihuahua who prior to my visit to the vet a week ago was the most happiest playful, and beautiful little boy I could ever hope for, he loved meal times and would eat everything I gave him. I’m sat here broke hearted. I have a 10 year old Alaskan Malamute. Some people don’t think of the monthly heartworm chewable pill containing ingredients that the dog may be allergic to. “The two most common neurological problems seem to be stroke and delirium.” Do not use this product. CAUTION : Guys , Border collies and few more dog breads are NOT supposed to be administered ADVOCATE !! As more people became infected, accounts of strokes and other neurological complications started coming in. A case report of 58 patients from France described neurological findings in 67% of patients (Helms, J., et al., The New England Journal of Medicine, Vol. Also after putting this treatment on she had wee’d on my floor which was were unusual too. Since this product contains the heartworm prevention medicine, it is dangerous to give this to your dog without a negative heartworm test. Other side effects can include loss of appetite, itching, biting or chewing at the application site, rash at the application site and lethargy. The vet had been saying that probably the dog wouldn’t survive and they were very upset. Hope he settles soon x, You may consider washing it off of him if you think he is having a reaction. He said it would be a safe option for her. Also, she is on an annual heart worm injection so would giving her Advocate be an overdose? Equimax®, Eqvalan®, Ivomec®, Noromectin®, Paramectin®, After reading here I will not be using on my gsd again . In my younger years, my family (sis, bro, parents) and I, between all of us, had a total of 10 purebred chihuahuas & one chihuahua cross. Perhaps someone with more knowledge than me could clarify this please. Best wishes to you and your dog. Speckles could not walk for about 2 months. I have a thirteen year old border collie who takes advocate. Years ago a Bayor product caused a serious illness ifor my mother-in-law and the medicine was taken off the market. Other concerned users advise that you thoroughly wash the product from the skin.Above all speak to your vet and draw his attention to this site.Particular problems with herding breeds eg collies on this site.Contact the maker,addresses on this site.HOPE YOUR DOG GETS WELL. Also not sure how old this post is. We took her to the vet and mentioned the Advocate the vet said usually only side effects would be a rash/itching at the site.She told us to bring her back next day she saw another vet and was kept in while they ran blood tests, these came back negative so we were told to take her to a large Vet company for a scan.The vets and she saw at least 4 there kept her in for a day ran more tests and decided to treat a brain disorder. Weir, K., & (2020, November). The list of possibility includes lungworms, ear mites and demodex mites. I came to this blog because I was going to give Advocate to my Afghan, and the previous times she had a bad reaction – listless, and obviously unhappy. https://www.bayer.com/en/contact.aspx. Listless, diarrhoea, vomiting and looks very low in mood. Be sure to discuss adding any other product with your Vet in order to avoid any problems with multiple product combinations. Your pet might also appear non-responsive, suffer from seizures, snap at the air, shake uncontrollably and have difficulty in breathing. He is a very active, healthy 14 year old, and the onset of these symptoms have to be related to the drug. “There’s a wide range of symptoms, including headaches, dizziness, weakness, confusion, eye movement problems, seizures and paralysis,” he says. Then the day before yesterday I applied not even a whole dose, maybe 2/3 of a tube as it’s not flea season and yesterday he was lethargic and couldn’t stand up, he had to be carried to the vets as his legs wouldn’t work. I use advocate on my dog.. and once put on the back of her neck she shakes her head and generally it sprays in the surrounding area.. what I haven’t read anywhere is the fact of what it does to the things it lands on if you don’t wipe it off straight away!!! Advocate does come with general warnings and contra indications anyway for all dogs. I hope you get some answers so your dog doesn’t have any more seizures. My dog had the second application of Advocate. My dog a border collie cross. FDA fact sheet about potential neurologic adverse events in dogs and cats when treated with the flea and tick drugs Bravecto, Credelio, Nexgard, or Simparica. THE ONLY REASON you need a prescription is like anything else in the US, profit, nothing to do with your dogs welfare; and no reason to need a prescription each time. My lovely 9 month lab/collie cross has been diagnosed today with SR meningitis. Q. Sad thing in all this is he has never used this product before, we were using another well known brand, which we have done so all along, this was only used because my vet recommended it to me, I now feel that I am in away responsible for his condition, the treatment was given to me as a single vial, no box and no warnings and I do feel that the vet should have been aware of possible side effects and informed me of them. I did some research and was horrified to learn that not only could the Advocate have done this but also caused his neurological problems last year. This product has a 35 day half life. Vet ( PDSA) him some injections and dog got worse on the way home and was taken back on saturday, we are now wednesday and no closer to knowing exactly what is wrong. They so wrong my dog now very ill. Hi Katherine, I don’t know how old this post is but my 7 month old dog is experiencing the same symptoms. I have spent the last day just crying because I can not believe what has happened to him x, My 6 month old staffy has advocate and over night has scratched the skin from his eyes and ears. We just went to the vet and he was just given again vitamin B injection and pain reliever for his muscle spasms. He hasn’t done this for years!!!! The information is for entertainment purposes only and should not be used to diagnose any problem or disease with your dog. He is totally lethargic and hyperventilating so we will definitely be looking for an alternative. She is taking epihen which seemed to help. Luckily I have a wonderful vet and This stuff is very toxic to small dogs under 9 lbs. I put it on the back of his neck in the morning and rest of that day everything was fine, in the morning he was his usual self! I hope to find enough people who this has happened to so we can form a class action lawsuit. In both cats and dogs the most common side effects are local reactions at the place where the product has been applied, such as temporary itchiness, and on rare occasions, greasy fur and redness of the skin. He ran and semed to panic .He salivated and looked like he was going to have a seizure. Many of these products have been discontinued because of such common reactions. The vet wanted to start her on medication for her seizures but I wanted to wait and see what happened. She developed idiopathic epilepsy last year. Just like any other product, there are pros and cons to Advocate. It is important to make sure that the right product is used, the FDA said. Plus she was a border collie. But your friend’s dog may just have hypersensitivity to the product as mentioned in the article. reason puppy was taken to vets ( hes 8 months old) is he couldnt get up, whne he did he fell back down as if legs gave way. This time after giving her Advocate, the next day odd behaviour that was most unlike her, and I was my normal self! Hi.. I’ve just read through these comments, as I had to rush my 1 year old border terrier to the vets yesterday after severe vomitting and poo’s and bleeding from her back passage. She had this reaction four months ago. With this medication, well. Other than when administering advocate we had never seen him like that. also too try and put it on after the bath 48 hours. As the months went on his reactions became progressively worse to the point my husband had to hold him in a corner while I put it on his neck. [email protected] I read other comments in this site and immediately washed it off with shampoo. Here is Bayer’s contact page https://www.bayer.com/en/contact.aspx, Best Regards, The prevalence of neurological problems remains an open question, but it’s safe to conclude that “neurological problems are not rare for COVID-19 patients,” says Majid Fotuhi, MD, PhD, medical director of NeuroGrow Brain Fitness Center and lead author of a comprehensive review of COVID-19’s effects on the nervous system (Journal of Alzheimer’s Disease, Vol. I rang Bayer & they advised me to stop using it & get a refund from my vet. He had literally scratched his fur off. The collaborative effort, endorsed by the Neurocritical Care Society, is collecting data and evaluating functional and cognitive outcomes to inform treatment strategies (Frontera, J., et al., Neurocritical Care, Vol. That’s when we noticed he tries to regurgitate but no vomit and he trembles and with muscle spasms. Thanks for sharing your story. Advocate for Dogs (also sold as “Advantage Multi” and both manufactured by Bayer) is a topical product that is designed to prevent heartworms, fleas and other internal and external parasitic infestations in dogs. The information contained on this site is the opinion soley of the authors. Washed it off and fingers crossed she is ok now. Took to vet this afternoon, they said could be neurological?? I wasn’t frightened , I was shocked and upset if I am being honest. Bravecto®, has been increasing in popularity due to the convenience and efficacy of its 12-week treatments; at the same time, however, this medication is also becoming popular for its adverse side effects and alleged deaths after administering the Bravecto® flea and tick treatment. Any advice please, I would wash the advocate off of him and contact your vet or the manufacturer – Bayer: https://www.bayer.com/en/contact.aspx. Its been 2hours since i gave the advocate and nothing unusual is happening. To be clear, you would need a *different* product to eliminate the rounds, not the application of this topical every 10 days. After three weeks on medication the panting and tremors have ceased and my dog is brighter and happier than I have ever seen him. Taxotere (docetaxel): Like Taxol, there is also a concern for severe allergic reaction, and hair loss will occur. He was referred to a Neuro centre for bloods and an MRI. She has had to have herr I’m not sure when this was done so I don’t know if she will see this but Carolyn if they didn’t tell you what was included in the puppy pack or at least have it posted then yes the vet is liable. Sorry to hear about your dog having seizures. In their review, Fotuhi and his colleagues describe the variety of neurological complications in patients with COVID-19. The only time you would not use all is maybe if your dog is at the low end of that weight range. Advancing psychology to benefit society and improve lives, delirium and other neurological side effects, Multimorbidity in Health Psychology and Behavioral Medicine Research, © 2021 American Psychological Association. Love my pup too much to let him suffer like this again. A study by scientists in England of 43 patients with severe neurological complications from COVID-19 found that some patients had relatively mild respiratory symptoms (Paterson, R.W., et al., Brain, published online, 2020). Thank you everyone for your comments it helps other dog owners to make decisions on these products, Hi Roberta my greyhound also tended to suffer from diarrhoea on a regular basis. Advocate can be beneficial in this situation because it is a topical – on-the-skin, treatment instead of oral. We have been using Advocate on our puppy basset hound for 4 months now, luckily no major side effects like some but I have noticed that whenever we put it on him he eats grass and vomits. 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